What is Umbilical Cord Blood?
Umbilical Cord Blood, also known as placental blood, is the blood that circulates in the developing fetus and remains in the placenta and in the attached umbilical cord after childbirth.
Umbilical Cord Blood contains a variety of cell types that have the capacity to differentiate into a wide variety of different cell types and may be frozen for later use in medical therapies, such as stem cell transplantation or regenerative medicine.
What is Umbilical Cord Tissue?
Another source of stem cells can be found in the umbilical cord aside from the blood – this being the cord tissue itself. The tissue of the umbilical cord is a rich source of stem cells, mainly Mesenchymal stem cells, Endothelial cells and Epithelial cells.
What is stem cell preservation?
Stem cell preservation consists of the long-term storage of stem cells, collected from different sources at a very low temperature in liquid nitrogen, for potential therapeutic applications. Similarly, umbilical cord blood banking is the practice of preserving fetal blood that remains in the umbilical cord at the time of birth for future use. Therefore, for banking purposes, stem cell preservation consists of collecting the cord blood from the placenta and umbilical cord after the baby is delivered. This is done by inserting a needle into the placental vein and allowing the cord blood to flow by gravity into a sterile, anti-coagulating blood-collection bag.
The tissue is easily collected by taking a section of the umbilical cord.
The collected samples are then sent to the “bank” in a special container designed for their appropriate transportation. The cells are processed and ultimately preserved by being frozen in liquid nitrogen for up to 25 years at -196 Celcius.
Why should we keep the baby’s stem cells?
After the baby’s birth, the umbilical cord and placenta is often discarded as biologic waste. Preserving the umbilical cord blood instead of throwing it away after the baby’s delivery allows the possibility of saving the baby’s cord stem cells for their own medical use or even for family members. Furthermore, the umbilical cord tissue represents a viable source of stem cells such as Mesenchymal stem cells, endothelial and epithelial stem cells which can be used to treat a wide range of medical problems, such as damaged tissue and organs, wounds and vascular damage, etc…
Umbilical Cord Banking
Ease and safe procurement
Umbilical Cord Blood is easily collected at the time of delivery without any risk or pain to either the newborn or the mother. Thus, it is an easy procedure performed without danger, which provides a rich source of stem cells.
Rapid access after storage
Your own cryopreserved stem cells are immediately available when needed and can be accessed at any time without the need of matching, unlike bone marrow which can be difficult to access.
Treatment of a variety of diseases
The rich source of stem cells can be used to treat a wide variety of diseases, including blood disorders, cancers and immune deficiencies. The list of such diseases is growing every year due to encouraging clinical results as researchers delve further into this fascinating field.
Low rejection risk
When the umbilical cord stem cells are used for transplantation, the potential risk of the body rejecting the cells is very low, and can be completely avoided. There is also a decreased viral transmission, which minimizes the risk of infection.
Which diseases can be treated by cord blood stem cells?
Research has proved that stem cells can be used not only in regenerating organs and repairing damaged muscle tissue and tendons, but also in treating leukemia and other malignant blood disorders.
|Acute lymphocytic leukemia||Chronic lymphocytic leukemia|
|Juvenile myelomonocytic leukemia||Myelodysplastic syndrome|
|Acute myeloid leukemia||Chronic myelogenous leukemia|
|Common variable immunodeficiency-myelodysplastic syndrome|
|Krabbe’s disease||Severe aplastic anemia|
|Amegakaryocytic thrombocytopenia||Global cell leukodystrophy|
|Langerhans cell histiocytosis||Severe combined immunodeficiency|
|Bare-leukocyte syndrome||Gunter disease|
|Lesch-Nyhan disease||Sickle cell disease|
|Blackfan-Diamond anemia||Hunter’s syndrome|
|Leukocyte adhesion defect||Thalassemia|
|Dyskeratosis congenita||Hurler’s syndrome|
|Neuronal ceroid lipofuscinosis||Wiskott-Aldrich syndrome|
|Familial erythrophagocytic lymphohistiocytosis||Kostmann’s syndrome|
|Osteopetrosis||X-linked lymphoproliferative disorder|
Ref: B. Anthony Armson, Umbilical Cord Blood Banking: Implications for Perinatal Care Providers, March 2005
Why REVIVA Regenerative Medicine Center?
- Proximity and accessibility
- Quality and Viability
- High standard Facility
- Cell therapy Center
- Storage of stem cells from different sources
Enrollment in REVIVA Regenerative Center program
Umbilical cord is used today to treat many life-threatening diseases
Potential therapeutic areas
- Heart attacks
- Skeletal disease and injury
- Autoimmune and inflammatory disease
- Heart and vascular disease
- Gastrointestinal disease
- Neurological disease and injury
- Wounds, burns and ulcers
- Ocular surface disease
- Vascular damage